Mitsuhiko Yamada Selected Research

Methamphetamine (Desoxyn)

8/2015	Associations between the orexin (hypocretin) receptor 2 gene polymorphism Val308Ile and nicotine dependence in genome-wide and subsequent association studies.
10/2011	No significant association between SIRT1 gene and methamphetamine-induced psychosis in the Japanese population.
8/2011	Lack of association between translin-associated factor X gene (TSNAX) and methamphetamine dependence in the Japanese population.
3/2011	Genetic Association Analysis of NOS1 and Methamphetamine-Induced Psychosis Among Japanese.
3/2011	No Association Between GRM3 and Japanese Methamphetamine-Induced Psychosis.
3/2011	Association analysis of the tryptophan hydroxylase 2 gene polymorphisms in patients with methamphetamine dependence/psychosis.
3/2011	Association analysis of the adenosine A1 receptor gene polymorphisms in patients with methamphetamine dependence/psychosis.
1/2011	Serotonin 6 receptor gene is associated with methamphetamine-induced psychosis in a Japanese population.
8/2010	The adenosine A2A receptor is associated with methamphetamine dependence/psychosis in the Japanese population.
5/2010	Association analysis of GRM2 and HTR2A with methamphetamine-induced psychosis and schizophrenia in the Japanese population.

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Mitsuhiko Yamada Research Topics

Disease

32	Psychotic Disorders (Schizoaffective Disorder) 08/2015 - 10/2004
18	Schizophrenia (Dementia Praecox) 03/2022 - 03/2005
12	Heart Failure 01/2022 - 01/2009
7	Major Depressive Disorder (Major Depressive Disorders) 01/2020 - 01/2006
7	Substance-Related Disorders (Drug Abuse) 03/2008 - 10/2004
5	Ventricular Tachycardia 01/2020 - 06/2008
4	Anxiety Disorders (Anxiety Disorder) 03/2019 - 01/2015
4	Mental Disorders (Mental Disorder) 11/2013 - 05/2009
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 10/2018
3	Ventricular Premature Complexes (Premature Ventricular Contraction) 01/2014 - 01/2011
3	Bipolar Disorder (Manic Depressive Psychosis) 08/2011 - 07/2005
3	Mood Disorders (Mood Disorder) 04/2010 - 07/2005
2	Hypertrophy 01/2021 - 01/2014
2	Tachycardia (Tachyarrhythmias) 01/2021 - 01/2011
2	Infarction (Infarctions) 04/2015 - 09/2003
2	Fibrosis (Cirrhosis) 01/2014 - 01/2012
2	Ischemia 01/2014 - 01/2011
2	Cardiac Arrhythmias (Arrythmia) 01/2014 - 01/2012
2	Genetic Predisposition to Disease (Genetic Predisposition) 03/2011 - 08/2010
2	Reperfusion Injury 06/2008 - 09/2003
1	Hypersensitivity (Allergy) 03/2022
1	Intellectual Disability (Idiocy) 01/2022
1	Muscular Diseases (Myopathy) 01/2022
1	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2022
1	Autism Spectrum Disorder 01/2022
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2021
1	Inflammation (Inflammations) 11/2020
1	Hyperplasia 11/2020
1	Neoplasms (Cancer) 09/2019
1	Chronic Renal Insufficiency 01/2019
1	Pain (Aches) 01/2019
1	Neuralgia (Stump Neuralgia) 01/2019
1	Hypertension (High Blood Pressure) 01/2019
1	Thrombosis (Thrombus) 01/2019
1	Tetanus 12/2018
1	Atrophy 12/2018
1	Catalepsy 04/2018
1	Atherosclerosis 01/2018
1	Weight Loss (Weight Reduction) 01/2017

Drug/Important Bio-Agent (IBA)

35	Methamphetamine (Desoxyn)FDA LinkGeneric 08/2015 - 10/2004
7	Antidepressive Agents (Antidepressants)IBA 09/2019 - 11/2008
5	Pharmaceutical PreparationsIBA 11/2020 - 03/2005
4	Riluzole FDA LinkGeneric 10/2015 - 01/2011
3	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 03/2022 - 01/2008
3	ArrestinIBA 01/2021 - 01/2017
3	KNT 127IBA 03/2019 - 01/2017
3	Purinergic P1 Receptors (Adenosine Receptor)IBA 02/2014 - 08/2010
3	Polyvinyl Chloride (PVC)IBA 01/2014 - 01/2011
3	Proteins (Proteins, Gene)FDA Link 04/2012 - 07/2005
3	Nicorandil (SG 75)IBA 01/2012 - 06/2008
3	EnzymesIBA 03/2011 - 03/2005
3	Adenosine Triphosphate (ATP)IBA 01/2011 - 09/2003
3	Dopamine (Intropin)FDA LinkGeneric 08/2008 - 10/2004
2	N-Methylaspartate (NMDA)IBA 03/2022 - 08/2009
2	GTP-Binding Proteins (G-Protein)IBA 01/2022 - 01/2009
2	Sar-Arg-Val-Tyr-Ile-His-Pro-Ala-OHIBA 01/2021 - 11/2020
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 06/2008
2	Isoproterenol (Isoprenaline)FDA LinkGeneric 01/2021 - 02/2014
2	CytokinesIBA 11/2020 - 01/2018
2	lysophosphatidic acidIBA 05/2019 - 01/2019
2	delta Opioid Receptors (delta Opioid Receptor)IBA 03/2019 - 07/2006
2	Sulfoglycosphingolipids (Sulfatides)IBA 01/2019 - 01/2019
2	Angiotensin IIIBA 01/2019 - 01/2014
2	Anti-Anxiety Agents (Anxiolytics)IBA 01/2015 - 01/2013
2	Cholinergic Agents (Cholinergics)IBA 02/2014 - 02/2002
2	Adrenergic Agents (Adrenergic Drugs)IBA 02/2014 - 03/2011
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 04/2012 - 03/2011
2	Glutamic Acid (Glutamate)FDA Link 03/2011 - 08/2009
2	A-factor (Streptomyces)IBA 03/2011 - 07/2006
2	Serotonin (5 Hydroxytryptamine)IBA 03/2011 - 02/2010
2	Diacylglycerol KinaseIBA 01/2011 - 01/2009
2	Monoamine Oxidase (MAO)IBA 05/2009 - 01/2004
2	DNA (Deoxyribonucleic Acid)IBA 10/2008 - 07/2006
1	Dizocilpine Maleate (Dizocilpine)IBA 03/2022
1	DystrophinIBA 01/2022
1	Protein Isoforms (Isoforms)IBA 01/2022
1	AldosteroneIBA 01/2021
1	Angiotensin Receptors (Angiotensin II Receptor)IBA 01/2021
1	Interleukin-13IBA 11/2020
1	KynurenineIBA 11/2020
1	InterleukinsIBA 11/2020
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2020
1	IvabradineIBA 01/2019
1	Lipoproteins (Lipoprotein)IBA 01/2019
1	ProstaglandinsIBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 01/2019
1	Antihypertensive Agents (Antihypertensives)IBA 01/2019
1	GlycosphingolipidsIBA 01/2019
1	Analgesics (Analgesic Drugs)IBA 01/2019
1	grapiprantIBA 01/2019
1	CalciumIBA 12/2018
1	4- (alpha- (4- allyl- 2,5- dimethyl- 1- piperazinyl)- 3- methoxybenzyl)- N,N- diethylbenzamideIBA 04/2018
1	Platelet-Derived Growth FactorIBA 01/2018

Therapy/Procedure

6	Therapeutics 01/2021 - 01/2015
2	Transplantation 01/2020 - 04/2015
2	Drug Therapy (Chemotherapy) 09/2019 - 01/2018
1	Nephrectomy 01/2019
1	Renal Dialysis (Hemodialysis) 01/2019
1	Oral Administration 01/2019
1	Denervation 12/2018